The Valve Wire sealThe Valve Wire
May 27, 2026E. Nolan Beckett, MD · Editor
LIVE · 14:39 ET · MAY 27, 2026
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Aortic Valve (TAVR/TAVI)Wednesday, May 27, 2026

Jefferies Financial Group Inc. Cuts Stake in Edwards Lifesciences Corporation $EW - MarketBeat

1 min read·By E. Nolan Beckett, MD·Source: MarketBeat
From The Valve Wire

The TAVR-explant problem is now a number we can quote at heart team meetings. [NOTABLE] A narrative review of four studies and 35,677 patients pegs operative mortality of redo SAVR after TAVR at 12-17% versus 1.1-9% after prior SAVR , with propensity-matched odds ratios as high as 12.5 and observed-to-expected ratios exceeding 1.0 even in low-risk patients.

TAVR-SAVR volume is growing at up to 144.6% annually and may eclipse SAVR-SAVR by 2029.

Editor’s take pending for this article; this is the section commentary excerpt.
Source Abstract

Jefferies Financial Group Inc. Cuts Stake in Edwards Lifesciences Corporation $EW MarketBeat

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