Trial Status Dashboard

Tracking the field

Current status of every structural heart trial in our coverage, including the 16 landmark trials The Valve Wire monitors continuously. Status changes between observations get flagged in the daily digest; this page is the always-on view.

28 trials tracked ・ Updated May 27, 2026, 12:20 PM UTC

← Daily digest Archive →

Trial	Status	Phase	Enrollment	Completion	Last update
Sapien 3 Transcatheter Aortic Valve Replacement in Young Aortic Valve Stenosis Patients From China NCT06830499	RECRUITING	N/A	450	2031-06-30	May 27, 2026
NHLBI-Emory Advanced Cardiac CT Reconstruction NCT05372627	NOT_YET_RECRUITING	N/A	1000	2031-01-30	May 27, 2026
A Feasibility Study of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral Regurgitation NCT04147884	ACTIVE_NOT_RECRUITING	NA	4	2026-11	May 27, 2026
Identifying Biological Markers of Cardiovascular Events in Patients With Aortic Stenosis or TAVI NCT06713889	RECRUITING	N/A	125	2030-06	May 27, 2026
TAVI in LOW RISK in the REAL WORLD NCT07605780	COMPLETED	N/A	650	2025-08-24	May 26, 2026
Transcatheter vs. Surgical Treatment of Degenerative Mitral Regurgitation NCT07605715	RECRUITING	N/A	60	2027-08	May 26, 2026
Navitor Japan Study NCT07193888	RECRUITING	N/A	100	2028-08	May 26, 2026
TRanscatheter Aortic-Valve Implantation Without On-site Cardiac Surgery NCT07604402	NOT_YET_RECRUITING	NA	1612	2034-05-30	May 22, 2026
A Multimodal Strategy to Screen for and Rule-Out Delayed High-Grade Conduction Disturbances After TAVR NCT07414485	COMPLETED	N/A	209	2026-04-23	May 22, 2026
Von Willebrand Factor Point-of-care Testing to Improve Minimally Invasive TAVI Outcomes NCT03728049	RECRUITING	NA	944	2026-12	May 22, 2026
Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System NCT06458907	NOT_YET_RECRUITING	NA	780	2032-11	May 22, 2026
Identification of Epigenetic Risk Factors for Ischemic Complication During the TAVR Procedure in the Elderly NCT02972008	RECRUITING	N/A	542	2027-02	May 22, 2026
EMPagliflozin After Aortic Valve Replacement NCT06171802	COMPLETED	PHASE4	206	2026-05-18	May 22, 2026
Diagnostic Study of Structural Heart Disease Based on Cardiac Electromechanical Signals NCT07603115	NOT_YET_RECRUITING	N/A	1300	2027-12	May 22, 2026
Reduction of Mitral Regurgitation With the SATURN Trans-Septal Transcatheter Mitral Valve Replacement (TMVR) System in Patients With Severe Symptomatic Mitral Regurgitation NCT06414265	RECRUITING	NA	30	2030-02	May 20, 2026
Routine Versus Selective Protamine Administration to Reduce Bleeding Complications After Transcatheter Aortic Valve Implantation (POPular ACE TAVI) NCT05774691	COMPLETED	PHASE4	1000	2026-01-02	May 20, 2026
Intrepid TMVR Pivotal LandmarkNCT03242642	RECRUITING	NA	1056	2036-09-30	May 19, 2026
REPAIR-MR (MitraClip vs surgery for primary MR) LandmarkNCT04198870	ACTIVE_NOT_RECRUITING	NA	500	2035-12	May 15, 2026
CLASP II TR (PASCAL for TR) LandmarkNCT04097145	RECRUITING	NA	1270	2031-12-31	May 8, 2026
Evolut Low Risk (long-term follow-up) LandmarkNCT02701283	ACTIVE_NOT_RECRUITING	NA	2223	2029-06	May 7, 2026
COAPT (MitraClip for secondary MR - long-term follow-up) LandmarkNCT03706833	ACTIVE_NOT_RECRUITING	NA	1247	2031-06-30	Apr 9, 2026
PRIMATY (MitraClip vs medical therapy for secondary MR) LandmarkNCT05051033	RECRUITING	NA	450	2030-11-15	Mar 3, 2026
TRISCEND II (Evoque tricuspid replacement) LandmarkNCT04482062	ACTIVE_NOT_RECRUITING	NA	864	2030-06-27	Feb 27, 2026
APOLLO (Tendyne TMVR) LandmarkNCT04101357	TERMINATED	PHASE1, PHASE2	54	2024-05-23	Mar 18, 2025
TRILUMINATE Pivotal (TriClip for TR) LandmarkNCT03904147	ACTIVE_NOT_RECRUITING	NA	572	2029-04	Dec 19, 2024
GATE Pivotal (NaviGate tricuspid replacement) LandmarkNCT05071768	COMPLETED	NA	31	2023-02-16	Jun 27, 2024
SAPIEN M3 TMVR Early Feasibility LandmarkNCT05490992	COMPLETED	NA	2448	2021-12-31	Feb 6, 2024
PARTNER 3 Low Risk (5-year follow-up) LandmarkNCT04728698	WITHDRAWN	PHASE2	0	2021-09	Sep 16, 2021

Source: ClinicalTrials.gov. The Valve Wire polls each tracked trial daily and surfaces material changes (status, phase, enrollment, completion date) in the morning digest.